Reaction Details  Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50536980
Substrate
n/a
Meas. Tech.
ChEMBL_1935276 (CHEMBL4481035)
Ki
29±n/a nM
Citation
 Intagliata, S; Alsharif, WF; Mesangeau, C; Fazio, N; Seminerio, M; Xu, YT; Matsumoto, RR; McCurdy, CR Benzimidazolone-based selective ? Eur J Med Chem 165:250-257 (2019) [PubMed]  Article
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50536980
Synonyms:
CHEMBL4573555
Type:
Small organic molecule
Emp. Form.:
C23H29Cl2FN4O2
Mol. Mass.:
483.406
SMILES:
Cl.Cl.CC(=O)c1ccc2n(CCCCN3CCN(CC3)c3ccc(F)cc3)c(=O)[nH]c2c1
Structure:
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