Reaction Details  Report a problem with these data
Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50539742
Substrate
n/a
Meas. Tech.
ChEMBL_1979106 (CHEMBL4612241)
Ki
>10000±n/a nM
Citation
 Kochanowska-Karamyan, AJ; Araujo, HC; Zhang, X; El-Alfy, A; Carvalho, P; Avery, MA; Holmbo, SD; Magolan, J; Hamann, MT Isolation and Synthesis of Veranamine, an Antidepressant Lead from the Marine Sponge  J Nat Prod 83:1092-1098 (2020) [PubMed]  Article
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50539742
Synonyms:
CHEMBL4642292
Type:
Small organic molecule
Emp. Form.:
C15H15BrN2
Mol. Mass.:
303.197
SMILES:
Cc1nccc2-c3ccc(Br)cc3NC(C)(C)c12
Structure:
Search PDB for entries with ligand similarity: