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Target
Mu-type opioid receptor
Ligand
BDBM50097583
Substrate
n/a
Meas. Tech.
ChEBML_145299
Ki
3000±n/a nM
Citation
Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM 8-Carboxamidocyclazocine analogues: redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Bioorg Med Chem Lett 11:623-6 (2001) [PubMed]
More Info.:
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
Inhibitor
Name:
BDBM50097583
Synonyms:
(6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid dimethylamide | CHEMBL346813
Type:
Small organic molecule
Emp. Form.:
C21H30N2O
Mol. Mass.:
326.4757
SMILES:
C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)N(C)C |TLB:8:9:1:14.12.13,15:14:1:9.4.3|