Reaction Details  Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50097585
Substrate
n/a
Meas. Tech.
ChEBML_145299
Ki
24±n/a nM
Citation
 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM 8-Carboxamidocyclazocine analogues: redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Bioorg Med Chem Lett 11:623-6 (2001) [PubMed]
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50097585
Synonyms:
(6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid methylamide | CHEMBL157301
Type:
Small organic molecule
Emp. Form.:
C20H28N2O
Mol. Mass.:
312.4491
SMILES:
CNC(=O)c1ccc2CC3[C@H](C)[C@](C)(CCN3CC3CC3)c2c1 |TLB:22:21:10:16.14.15,17:16:10:21.7.8|
Structure:
Search PDB for entries with ligand similarity: