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Target
Mu-type opioid receptor
Ligand
BDBM50542608
Substrate
n/a
Meas. Tech.
ChEMBL_1987296 (CHEMBL4620843)
Ki
1481±n/a nM
Citation
 He, G; Song, Q; Wang, J; Xu, A; Peng, K; Zhu, Q; Xu, Y Design, synthesis and biological evaluation of N-hydroxy-aminobenzyloxyarylamide analogues as novel selective ? opioid receptor antagonists. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50542608
Synonyms:
CHEMBL4638966
Type:
Small organic molecule
Emp. Form.:
C26H26N2O3
Mol. Mass.:
414.4962
SMILES:
Cc1cc(C)cc(c1)C1CCCN1Cc1ccc(Oc2ccc3c(c2)o[nH]c3=O)cc1
Structure:
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