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Target
Cannabinoid receptor 1
Ligand
BDBM50543755
Substrate
n/a
Meas. Tech.
ChEMBL_1989774 (CHEMBL4623509)
Ki
14±n/a nM
Citation
 Brizzi, A; Aiello, F; Boccella, S; Cascio, MG; De Petrocellis, L; Frosini, M; Gado, F; Ligresti, A; Luongo, L; Marini, P; Mugnaini, C; Pessina, F; Corelli, F; Maione, S; Manera, C; Pertwee, RG; Di Marzo, V Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity. Bioorg Med Chem 28:0 (2020) [PubMed]  Article
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50543755
Synonyms:
CHEMBL4638147
Type:
Small organic molecule
Emp. Form.:
C28H45NO3
Mol. Mass.:
443.6618
SMILES:
CCCCCc1cc(OCCCCCCCCCCC(=O)NC2CC2)cc(OCC=C)c1
Structure:
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