Reaction Details  Report a problem with these data
Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50546079
Substrate
n/a
Meas. Tech.
ChEMBL_2014077 (CHEMBL4667655)
Ki
2480±n/a nM
Citation
 Ahn, S; Kim, J; An, S; Pyo, JJ; Jung, D; Lee, J; Hwang, SY; Gong, J; Shin, I; Kim, HP; Kim, H; Noh, M 2-Phenyl-8-(1-phenylallyl)-chromenone compounds have a pan-PPAR modulator pharmacophore. Bioorg Med Chem 27:2948-2958 (2019) [PubMed]  Article
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50546079
Synonyms:
CHEMBL4746258
Type:
Small organic molecule
Emp. Form.:
C25H20O6
Mol. Mass.:
416.4227
SMILES:
COc1cc(ccc1O)C(C=C)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1
Structure:
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