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Target
Superoxide dismutase [Cu-Zn]
Ligand
BDBM50550532
Substrate
n/a
Meas. Tech.
ChEMBL_2027628 (CHEMBL4681786)
IC50
46600±n/a nM
Citation
 Moreno-Viguri, E; Jiménez-Montes, C; Martín-Escolano, R; Santivañez-Veliz, M; Martin-Montes, A; Azqueta, A; Jimenez-Lopez, M; Zamora Ledesma, S; Cirauqui, N; López de Ceráin, A; Marín, C; Sánchez-Moreno, M; Pérez-Silanes, S In Vitro and in Vivo Anti-Trypanosoma cruzi Activity of New Arylamine Mannich Base-Type Derivatives. J Med Chem 59:10929-10945 (2016) [PubMed]  Article
Target
Name:
Superoxide dismutase [Cu-Zn]
Synonyms:
SOD1 | SODC_HUMAN | Superoxide dismutase
Type:
PROTEIN
Mol. Mass.:
15933.55
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1444880
Residue:
154
Sequence:
MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
  
Inhibitor
Name:
BDBM50550532
Synonyms:
CHEMBL1782791
Type:
Small organic molecule
Emp. Form.:
C21H21N3O3S
Mol. Mass.:
395.475
SMILES:
[O-][N+](=O)c1ccc(cc1)N1CCN(CCC(=O)c2csc3ccccc23)CC1
Structure:
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