Reaction Details  Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM50552448
Substrate
n/a
Meas. Tech.
ChEMBL_2034393 (CHEMBL4688551)
Ki
30±n/a nM
Citation
 Onyameh, EK; Bricker, BA; Eyunni, SVK; Voshavar, C; Gonela, UM; Ofori, E; Jenkins, A; Ablordeppey, SY A study of the structure-affinity relationship in SYA16263; is a D Bioorg Med Chem 30:0 (2021) [PubMed]  Article
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50552448
Synonyms:
CHEMBL4793296
Type:
Small organic molecule
Emp. Form.:
C21H24FN3O5
Mol. Mass.:
417.4308
SMILES:
OC(=O)C(O)=O.Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cccnc1
Structure:
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