Reaction Details  Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM423299
Substrate
n/a
Meas. Tech.
ChEMBL_2054918 (CHEMBL4709919)
Ki
>1000±n/a nM
Citation
 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Isoquinolinone derivatives as potent CNS multi-receptor D Eur J Med Chem 207:0 (2020) [PubMed]  Article
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM423299
Synonyms:
US10501452, Compound 5
Type:
Small organic molecule
Emp. Form.:
C25H28FN3O3
Mol. Mass.:
437.5065
SMILES:
CN1CCc2ccc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2C1=O
Structure:
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