Target

Ligand

Substrate

Meas. Tech.

ChEMBL_2054934 (CHEMBL4709935)

Citation

 ?a?ewska, D; Bajda, M; Kaleta, M; Zar?ba, P; Doroz-P?onka, A; Siwek, A; Alachkar, A; Mogilski, S; Saad, A; Kuder, K; Olejarz-Maciej, A; Gody?, J; Stary, D; Sudo?, S; Wi?cek, M; Latacz, G; Walczak, M; Handzlik, J; Sadek, B; Malawska, B; Kie?-Kononowicz, K Rational design of new multitarget histamine H Eur J Med Chem 207:0 (2020) [PubMed]  Article

More Info.:

Get all data from this article,  Assay Method

Name:

Acetylcholinesterase

Synonyms:

ACES_ELEEL | Acetylcholinesterase (AChE) | Acetylcholinesterase (EeAChE) | ache

Type:

Enzyme

Mol. Mass.:

71812.79

Organism:

Electrophorus electricus (Electric eel)

Description:

n/a

Residue:

633

Sequence:

MKILDALLFPVIFIMFFIHLSIAQTDPELTIMTRLGQVQGTRLPVPDRSHVIAFLGIPFAEPPLGKMRFKPPEPKKPWNDVFDARDYPSACYQYVDTSYPGFSGTEMWNPNRMMSEDCLYLNVWVPATPRPHNLTVMVWIYGGGFYSGSSSLDVYDGRYLAHSEKVVVVSMNYRVSAFGFLALNGSAEAPGNVGLLDQRLALQWVQDNIHFFGGNPKQVTIFGESAGAASVGMHLLSPDSRPKFTRAILQSGVPNGPWRTVSFDEARRRAIKLGRLVGCPDGNDTDLIDCLRSKQPQDLIDQEWLVLPFSGLFRFSFVPVIDGVVFPDTPEAMLNSGNFKDTQILLGVNQNEGSYFLIYGAPGFSKDNESLITREDFLQGVKMSVPHANEIGLEAVILQYTDWMDEDNPIKNREAMDDIVGDHNVVCPLQHFAKMYAQYSILQGQTGTASQGNLGWGNSGSASNSGNSQVSVYLYMFDHRASNLVWPEWMGVIHGYEIEFVFGLPLEKRLNYTLEEEKLSRRMMKYWANFARTGNPNINVDGSIDSRRRWPVFTSTEQKHVGLNTDSLKVHKGLKSQFCALWNRFLPRLLNVTENIDDAERQWKAEFHRWSSYMMHWKNQFDHYSKQERCTNL

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM50556135

Synonyms:

CHEMBL4747044

Type:

Small organic molecule

Emp. Form.:

C25H30ClNO3

Mol. Mass.:

427.964

SMILES:

Clc1ccc2oc3ccc(OCCCCCCN4CCCCCC4)cc3c(=O)c2c1

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least: