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Target
Delta-type opioid receptor
Ligand
BDBM50120214
Substrate
n/a
Meas. Tech.
ChEBML_147145
Ki
>10000±n/a nM
Citation
 Rinnová, M; Nefzi, A; Houghten, RA Opioid activity of 4-imidazolidinone positional analogues of Leu-Enkephalin. Bioorg Med Chem Lett 12:3175-8 (2002) [PubMed]
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50120214
Synonyms:
(1S,4S)-2-[3-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetyl)-4-benzyl-5-oxo-imidazolidin-1-yl]-4-methyl-pentanoic acid amide | CHEMBL106101
Type:
Small organic molecule
Emp. Form.:
C29H38N6O6
Mol. Mass.:
566.6486
SMILES:
CC(C)C[C@H](N1CN([C@@H](Cc2ccccc2)C1=O)C(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O
Structure:
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