Reaction Details  Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50562173
Substrate
n/a
Meas. Tech.
ChEMBL_2077638 (CHEMBL4733429)
Ki
956±n/a nM
Citation
 Xie, XY; Li, YY; Ma, WH; Chen, AF; Sun, YT; Lee, JY; Riad, A; Xu, DH; Mach, RH; Huang, YS Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective ? Eur J Med Chem 209:0 (2021) [PubMed]  Article
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50562173
Synonyms:
CHEMBL4778965
Type:
Small organic molecule
Emp. Form.:
C25H33NO7
Mol. Mass.:
459.532
SMILES:
COc1cc2CCN(CCC(=O)c3c(C)c(OC)c(OC)c(OC)c3OC)Cc2cc1OC
Structure:
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