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Target
Cyclin-O
Ligand
BDBM50563177
Substrate
n/a
Meas. Tech.
ChEMBL_2081665 (CHEMBL4737456)
IC50
42±n/a nM
Citation
 Lee, JC; Hong, KH; Becker, A; Tash, JS; Schönbrunn, E; Georg, GI Tetrahydroindazole inhibitors of CDK2/cyclin complexes. Eur J Med Chem 214:0 (2021) [PubMed]  Article
Target
Name:
Cyclin-O
Synonyms:
CCNO | CCNO_HUMAN | CDK2/Cyclin O | Cyclin-O
Type:
PROTEIN
Mol. Mass.:
38106.14
Organism:
Homo sapiens
Description:
ChEMBL_117722
Residue:
350
Sequence:
MVTPCPTSPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDLFESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFRKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRLGDHPEAALEDCMGKLQLLVAINSTSLTHMLPVQICEKCSLPPSSK
  
Inhibitor
Name:
BDBM50563177
Synonyms:
CHEMBL4763182
Type:
Small organic molecule
Emp. Form.:
C14H15BrN4O
Mol. Mass.:
335.199
SMILES:
Cc1nn(c2C(Br)C(C)(C)CC(=O)c12)-c1ccncn1
Structure:
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