Reaction Details  Report a problem with these data
Target
Neuropeptide Y receptor type 4
Ligand
BDBM50563420
Substrate
n/a
Meas. Tech.
ChEMBL_2082434 (CHEMBL4738225)
IC50
4000±n/a nM
Citation
 Schüß, C; Vu, O; Schubert, M; Du, Y; Mishra, NM; Tough, IR; Stichel, J; Weaver, CD; Emmitte, KA; Cox, HM; Meiler, J; Beck-Sickinger, AG Highly Selective Y J Med Chem 64:2801-2814 (2021) [PubMed]  Article
Target
Name:
Neuropeptide Y receptor type 4
Synonyms:
NPY-Y4 | NPY4-R | NPY4R | NPY4R_HUMAN | PP1 | PPYR1 | Pancreatic polypeptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42207.58
Organism:
Homo sapiens (Human)
Description:
NPY-Y4 PPYR1 HUMAN::P50391
Residue:
375
Sequence:
MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRRLQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTEVSKGSLRLSGRSNPI
  
Inhibitor
Name:
BDBM50563420
Synonyms:
CHEMBL4780125
Type:
Small organic molecule
Emp. Form.:
C16H19N3O5S2
Mol. Mass.:
397.469
SMILES:
CS(=O)(=O)N1CCCCC1C(=O)Nc1nc2cc3OCCOc3cc2s1
Structure:
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