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Target
Estrogen receptor
Ligand
BDBM50128415
Substrate
n/a
Meas. Tech.
ChEBML_67497
IC50
550±n/a nM
Citation
 Sibley, R; Hatoum-Mokdad, H; Schoenleber, R; Musza, L; Stirtan, W; Marrero, D; Carley, W; Xiao, H; Dumas, J A novel estrogen receptor ligand template. Bioorg Med Chem Lett 13:1919-22 (2003) [PubMed]
Target
Name:
Estrogen receptor
Synonyms:
ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1
Type:
Protein
Mol. Mass.:
66230.44
Organism:
Homo sapiens (Human)
Description:
P03372
Residue:
595
Sequence:
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
  
Inhibitor
Name:
BDBM50128415
Synonyms:
4-((1R,2R,5S)-5-Hydroxymethyl-bicyclo[3.3.1]non-7-en-2-yl)-phenol | CHEMBL57150
Type:
Small organic molecule
Emp. Form.:
C16H20O2
Mol. Mass.:
244.3288
SMILES:
OC[C@]12CC[C@H]([C@H](C1)C=CC2)c1ccc(O)cc1 |c:9|
Structure:
Search PDB for entries with ligand similarity: