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Target
D(4) dopamine receptor
Ligand
BDBM50568914
Substrate
n/a
Meas. Tech.
ChEMBL_2106946 (CHEMBL4815621)
Ki
14±n/a nM
Citation
 Ofori, E; Onyameh, EK; Gonela, UM; Voshavar, C; Bricker, B; Swanson, TL; Eshleman, AJ; Schmachtenberg, JL; Bloom, SH; Janowsky, AJ; Ablordeppey, SY New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263. Eur J Med Chem 214:0 (2021) [PubMed]  Article
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50568914
Synonyms:
CHEMBL4874069
Type:
Small organic molecule
Emp. Form.:
C22H27N3O
Mol. Mass.:
349.4693
SMILES:
O=C(CCCN1CCN(CC1)c1ccccn1)c1ccc2CCCc2c1
Structure:
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