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Target
Protein tyrosine phosphatase type IVA 3
Ligand
BDBM50569362
Substrate
n/a
Meas. Tech.
ChEMBL_2109174 (CHEMBL4817849)
IC50
26010±n/a nM
Citation
 Lin, L; Lu, L; Yuan, C; Wang, A; Zhu, M; Fu, X; Xing, S The dual inhibition against the activity and expression of tyrosine phosphatase PRL-3 from a rhodanine derivative. Bioorg Med Chem Lett 41:0 (2021) [PubMed]  Article
Target
Name:
Protein tyrosine phosphatase type IVA 3
Synonyms:
PRL3 | PTP4A3 | Protein-tyrosine phosphatase 4A3 | TP4A3_HUMAN
Type:
PROTEIN
Mol. Mass.:
19546.22
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461022
Residue:
173
Sequence:
MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
  
Inhibitor
Name:
BDBM50569362
Synonyms:
CHEMBL1699070
Type:
Small organic molecule
Emp. Form.:
C10H5Cl2NOS2
Mol. Mass.:
290.189
SMILES:
Clc1ccc(Cl)c(\C=C2/SC(=S)NC2=O)c1
Structure:
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