Reaction Details  Report a problem with these data
Target
Somatostatin receptor type 5
Ligand
BDBM50136791
Substrate
n/a
Meas. Tech.
ChEMBL_200855 (CHEMBL807064)
IC50
30±n/a nM
Citation
 Erchegyi, J; Waser, B; Schaer, JC; Cescato, R; Brazeau, JF; Rivier, J; Reubi, JC Novel sst(4)-selective somatostatin (SRIF) agonists. 3. Analogues amenable to radiolabeling. J Med Chem 46:5597-605 (2003) [PubMed]  Article
Target
Name:
Somatostatin receptor type 5
Synonyms:
SOMATOSTATIN SST5 | SS-5-R | SS5-R | SS5R | SSR5_HUMAN | SSTR5 | Somatostatin receptor type 5 (SSTR5)
Type:
Enzyme
Mol. Mass.:
39218.02
Organism:
Homo sapiens (Human)
Description:
P35346
Residue:
364
Sequence:
MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL
  
Inhibitor
Name:
BDBM50136791
Synonyms:
(S)-25-Amino-19-(4-amino-benzyl)-13-(4-amino-butyl)-7,22-dibenzyl-10-((S)-1-hydroxy-ethyl)-16-(1H-indol-3-ylmethyl)-6,9,12,15,18-penta(S)-oxo-21-(R)-oxo-24-oxo-1,2-dithia-5,8,11,14,17,20,23-heptaaza-cyclohexacosane-4-carboxylic acid | CHEMBL439902
Type:
Small organic molecule
Emp. Form.:
C54H67N11O10S2
Mol. Mass.:
1094.307
SMILES:
C[C@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(N)cc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O
Structure:
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