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Target
N-alpha-acetyltransferase 40
Ligand
BDBM50580965
Substrate
n/a
Meas. Tech.
ChEMBL_2149514 (CHEMBL5033912)
IC50
>20000±n/a nM
Citation
 Ding, H; Pei, Y; Li, Y; Xu, W; Mei, L; Hou, Z; Guang, Y; Cao, L; Li, P; Cao, H; Bian, J; Chen, K; Luo, C; Zhou, B; Zhang, T; Li, Z; Yang, Y Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer. Bioorg Med Chem 52:0 (2021) [PubMed]  Article
Target
Name:
N-alpha-acetyltransferase 40
Synonyms:
2.3.1.257 | N-acetyltransferase 11 | N-alpha-acetyltransferase 40 | N-alpha-acetyltransferase D | NAA40 | NAA40_HUMAN | NAT11 | NatD | PATT1 | Protein acetyltransferase 1 | Synonyms=NAT11 | hNatD
Type:
PROTEIN
Mol. Mass.:
27197.65
Organism:
Homo sapiens
Description:
ChEMBL_119123
Residue:
237
Sequence:
MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSVPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRTKFGDSHHSHAGGHCGGCCH
  
Inhibitor
Name:
BDBM50580965
Synonyms:
CHEMBL5090239
Type:
Small organic molecule
Emp. Form.:
C27H27FN4O6
Mol. Mass.:
522.5249
SMILES:
CNC(=O)Nc1ccc2c(CC[C@@]22OC(=O)N(CC(=O)N3Cc4cc(F)ccc4OC[C@H]3C3CC3)C2=O)c1 |r|
Structure:
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