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Target
N-alpha-acetyltransferase 40
Ligand
BDBM50581151
Substrate
n/a
Meas. Tech.
ChEMBL_2149892 (CHEMBL5034354)
Ki
8.7±n/a nM
Citation
 Deng, Y; Deng, S; Ho, YH; Gardner, SM; Huang, Z; Marmorstein, R; Huang, R Novel Bisubstrate Inhibitors for Protein N-Terminal Acetyltransferase D. J Med Chem 64:8263-8271 (2021) [PubMed]  Article
Target
Name:
N-alpha-acetyltransferase 40
Synonyms:
2.3.1.257 | N-acetyltransferase 11 | N-alpha-acetyltransferase 40 | N-alpha-acetyltransferase D | NAA40 | NAA40_HUMAN | NAT11 | NatD | PATT1 | Protein acetyltransferase 1 | Synonyms=NAT11 | hNatD
Type:
PROTEIN
Mol. Mass.:
27197.65
Organism:
Homo sapiens
Description:
ChEMBL_119123
Residue:
237
Sequence:
MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSVPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRTKFGDSHHSHAGGHCGGCCH
  
Inhibitor
Name:
BDBM50581151
Synonyms:
CHEMBL5077510
Type:
Small organic molecule
Emp. Form.:
C40H69N16O23P3S
Mol. Mass.:
1267.056
SMILES:
C[C@H](NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)CCSCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](OP(O)(O)=O)[C@@H]1O)n1cnc2c(N)ncnc12)C(N)=O |r|
Structure:
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