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Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM50152864
Substrate
n/a
Meas. Tech.
ChEMBL_305906 (CHEMBL832621)
IC50
7100±n/a nM
Citation
 Lehmann, F; Haile, S; Axen, E; Medina, C; Uppenberg, J; Svensson, S; Lundbäck, T; Rondahl, L; Barf, T Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target. Bioorg Med Chem Lett 14:4445-8 (2004) [PubMed]  Article
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM50152864
Synonyms:
3-(5-Methyl-indole-1-sulfonyl)-thiophene-2-carboxylic acid | CHEMBL360007
Type:
Small organic molecule
Emp. Form.:
C14H11NO4S2
Mol. Mass.:
321.371
SMILES:
Cc1ccc2n(ccc2c1)S(=O)(=O)c1ccsc1C(O)=O
Structure:
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