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Target
C-C motif chemokine 5
Ligand
BDBM50585055
Substrate
n/a
Meas. Tech.
ChEMBL_2161477 (CHEMBL5046338)
Kd
5720±n/a nM
Citation
 Shanthamurthy, CD; Leviatan Ben-Arye, S; Kumar, NV; Yehuda, S; Amon, R; Woods, RJ; Padler-Karavani, V; Kikkeri, R Heparan Sulfate Mimetics Differentially Affect Homologous Chemokines and Attenuate Cancer Development. J Med Chem 64:3367-3380 (2021) [PubMed]  Article
Target
Name:
C-C motif chemokine 5
Synonyms:
CCL5 | CCL5_HUMAN | D17S136E | EoCP | Eosinophil chemotactic cytokine | RANTES(3-68) | RANTES(4-68) | SCYA5 | SIS-delta | Small-inducible cytokine A5 | T cell-specific protein P228 | T-cell-specific protein RANTES | TCP228
Type:
PROTEIN
Mol. Mass.:
9996.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1363187
Residue:
91
Sequence:
MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS
  
Inhibitor
Name:
BDBM50585055
Synonyms:
CHEMBL5081237
Type:
Small organic molecule
Emp. Form.:
C28H43NO41S5
Mol. Mass.:
1209.948
SMILES:
[H][C@@]1(O[C@H]2[C@H](O)[C@@H](OS(O)(=O)=O)[C@H](OCCOCCN)O[C@H]2C(O)=O)O[C@H]([C@@H](O[C@]2([H])O[C@H]([C@@H](O[C@]3([H])O[C@H]([C@@H](OS(O)(=O)=O)[C@H](O)[C@H]3OS(O)(=O)=O)C(O)=O)[C@H](O)[C@H]2OS(O)(=O)=O)C(O)=O)[C@H](O)[C@H]1OS(O)(=O)=O)C(O)=O |r|
Structure:
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