Reaction Details  Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50585430
Substrate
n/a
Meas. Tech.
ChEMBL_2162476 (CHEMBL5047337)
Ki
70±n/a nM
Citation
 Abatematteo, FS; Mosier, PD; Niso, M; Brunetti, L; Berardi, F; Loiodice, F; Contino, M; Delprat, B; Maurice, T; Laghezza, A; Abate, C Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (? Eur J Med Chem 228:0 (2022) [PubMed]  Article
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50585430
Synonyms:
CHEMBL5094446
Type:
Small organic molecule
Emp. Form.:
C14H21Cl2NO
Mol. Mass.:
290.229
SMILES:
Cl.C[C@H]1CCCCN1CCOc1ccc(Cl)cc1 |r|
Structure:
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