Reaction Details  Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM50080995
Substrate
n/a
Meas. Tech.
ChEMBL_302635 (CHEMBL839926)
Ki
13200000±n/a nM
Citation
 Rusconi, S; Innocenti, A; Vullo, D; Mastrolorenzo, A; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet. Bioorg Med Chem Lett 14:5763-7 (2004) [PubMed]  Article
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50080995
Synonyms:
CHEMBL1060 | Dibasic sodium phosphate | Disodium phosphate | Na2HPO4 | disodium acid orthophosphate | disodium hydrogen phosphate | disodium hydrogenphosphate | disodium monohydrogen phosphate
Type:
Small organic molecule
Emp. Form.:
HO4P
Mol. Mass.:
95.9804
SMILES:
OP([O-])([O-])=O
Structure:
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