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Target
M-phase inducer phosphatase 2
Ligand
BDBM50589180
Substrate
n/a
Meas. Tech.
ChEMBL_2192291 (CHEMBL5104651)
IC50
19000±n/a nM
Citation
 Gozari, M; Alborz, M; El-Seedi, HR; Jassbi, AR Chemistry, biosynthesis and biological activity of terpenoids and meroterpenoids in bacteria and fungi isolated from different marine habitats. Eur J Med Chem 210:0 (2021) [PubMed]  Article
Target
Name:
M-phase inducer phosphatase 2
Synonyms:
CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN
Type:
Protein
Mol. Mass.:
64985.27
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
  
Inhibitor
Name:
BDBM50589180
Synonyms:
CHEMBL5192066
Type:
Small organic molecule
Emp. Form.:
C27H36O8
Mol. Mass.:
488.5699
SMILES:
[H][C@]12C[C@@]3(C)[C@@]([H])(C=C(C)[C@@]4(C)[C@](C)(O)C(=O)[C@@]34C(=O)OC)[C@@]3(CC[C@H](OC(C)=O)C(C)(C)[C@@]13[H])C(=O)O2 |r,t:7,TLB:36:35:5.3.2:33|
Structure:
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