Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50590328
Substrate
n/a
Meas. Tech.
ChEMBL_2196297 (CHEMBL5108813)
Ki
6.5±n/a nM
Citation
 Sparkes, E; Cairns, EA; Kevin, RC; Lai, F; Grafinger, KE; Chen, S; Deventer, MH; Ellison, R; Boyd, R; Martin, LJ; McGregor, IS; Gerona, RR; Hibbs, DE; Auwärter, V; Glass, M; Stove, C; Banister, SD Structure-activity relationships of valine,  RSC Med Chem 13:156-174 (2022) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50590328
Synonyms:
CHEMBL5180182
Type:
Small organic molecule
Emp. Form.:
C17H24N4O2
Mol. Mass.:
316.3981
SMILES:
CCCCn1nc(C(=O)N[C@@H](C(C)C)C(N)=O)c2ccccc12 |r|
Structure:
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