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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50594971
Substrate
n/a
Meas. Tech.
ChEMBL_2214837 (CHEMBL5127969)
EC50
285±n/a nM
Citation
 Chen, L; Yan, G; Ohwada, T Building on endogenous lipid mediators to design synthetic receptor ligands. Eur J Med Chem 231:0 (2022) [PubMed]  Article
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor
Type:
Enzyme
Mol. Mass.:
41834.57
Organism:
Homo sapiens (Human)
Description:
P34995
Residue:
402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
  
Inhibitor
Name:
BDBM50594971
Synonyms:
15-AU-81 | 15AU81 | CHEBI:50861 | L-606 | LRX -15 | LRX-15 | Remodulin | Rumodolin | TREPROSTINIL | Treprostinil | Tresprostinil | Tyvaso | Tyvaso dpi | UT-15 | Uniprost
Type:
Small organic molecule
Emp. Form.:
C23H34O5
Mol. Mass.:
390.5131
SMILES:
[H][C@]12C[C@@H](O)[C@H](CC[C@@H](O)CCCCC)[C@@]1([H])Cc1cccc(OCC(O)=O)c1C2
Structure:
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