Reaction Details  Report a problem with these data
Target
Parkinson disease protein 7
Ligand
BDBM50448804
Substrate
n/a
Meas. Tech.
ChEMBL_2223715 (CHEMBL5137228)
IC50
701±n/a nM
Citation
 Maksimovic, I; Finkin-Groner, E; Fukase, Y; Zheng, Q; Sun, S; Michino, M; Huggins, DJ; Myers, RW; David, Y Deglycase-activity oriented screening to identify DJ-1 inhibitors. RSC Med Chem 12:1232-1238 (2021) [PubMed]  Article
Target
Name:
Parkinson disease protein 7
Synonyms:
3.1.2.- | 3.5.1.- | 3.5.1.124 | DJ-1 | Maillard deglycase | Oncogene DJ1 | PARK7 | PARK7_HUMAN | Parkinsonism-associated deglycase | Protein DJ-1 | Protein/nucleic acid deglycase DJ-1
Type:
PROTEIN
Mol. Mass.:
19891.33
Organism:
Homo sapiens
Description:
ChEMBL_120727
Residue:
189
Sequence:
MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLKD
  
Inhibitor
Name:
BDBM50448804
Synonyms:
CHEMBL3128205
Type:
Small organic molecule
Emp. Form.:
C16H13NO2
Mol. Mass.:
251.2799
SMILES:
O=C1N(CCc2ccccc2)c2ccccc2C1=O
Structure:
Search PDB for entries with ligand similarity: