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Target
Prostaglandin D2 receptor
Ligand
BDBM50174355
Substrate
n/a
Meas. Tech.
ChEMBL_320830 (CHEMBL871672)
Ki
>10000±n/a nM
Citation
 Armer, RE; Ashton, MR; Boyd, EA; Brennan, CJ; Brookfield, FA; Gazi, L; Gyles, SL; Hay, PA; Hunter, MG; Middlemiss, D; Whittaker, M; Xue, L; Pettipher, R Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2. J Med Chem 48:6174-7 (2005) [PubMed]  Article
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50174355
Synonyms:
CHEMBL194019 | [1-(1,2-Dimethyl-1H-imidazole-4-sulfonyl)-5-fluoro-2-methyl-1H-indol-3-yl]-acetic acid
Type:
Small organic molecule
Emp. Form.:
C16H16FN3O4S
Mol. Mass.:
365.379
SMILES:
Cc1nc(cn1C)S(=O)(=O)n1c(C)c(CC(O)=O)c2cc(F)ccc12
Structure:
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