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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50101979
Substrate
n/a
Meas. Tech.
ChEMBL_2231111 (CHEMBL5144883)
IC50
5620±n/a nM
Citation
 Lefin, R; Petzer, A; Petzer, JP Phenothiazine, anthraquinone and related tricyclic derivatives as inhibitors of monoamine oxidase. Bioorg Med Chem 54:0 (2022) [PubMed]  Article
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50101979
Synonyms:
2,6-Dihydroxyanthraquinone | 2,6-dihydroxy-9,10-anthracenedione | 2,6-dihydroxy-9,10-anthraquinone | 2,6-dihydroxyanthra-9,10-quinone | 2,6-dihydroxyanthracene-9,10-dione | Az-F | CHEMBL298398 | anthraflavic acid | anthraflavin
Type:
Small organic molecule
Emp. Form.:
C14H8O4
Mol. Mass.:
240.2109
SMILES:
Oc1ccc2C(=O)c3cc(O)ccc3C(=O)c2c1
Structure:
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