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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50240382
Substrate
n/a
Meas. Tech.
ChEMBL_2231115 (CHEMBL5144887)
Ki
39±n/a nM
Citation
 Lefin, R; Petzer, A; Petzer, JP Phenothiazine, anthraquinone and related tricyclic derivatives as inhibitors of monoamine oxidase. Bioorg Med Chem 54:0 (2022) [PubMed]  Article
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA)
Type:
Protein
Mol. Mass.:
59689.53
Organism:
Homo sapiens (Human)
Description:
P21397
Residue:
527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
  
Inhibitor
Name:
BDBM50240382
Synonyms:
1,4-Dihydroxyanthrachinon | 1,4-dihydroxy-9,10-anthraquinone | 1,4-dihydroxyanthra-9,10-quinone | 1,4-dihydroxyanthracene-9,10-dione | 1,4-dihydroxyanthraquinone | CHEMBL17594 | Chinizarin | quinizarin | quinizarine
Type:
Small organic molecule
Emp. Form.:
C14H8O4
Mol. Mass.:
240.2109
SMILES:
Oc1ccc(O)c2C(=O)c3ccccc3C(=O)c12
Structure:
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