Reaction Details 
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Report a problem with these dataTarget
D(2) dopamine receptor
Ligand
BDBM50599915
Substrate
n/a
Meas. Tech.
ChEMBL_2232050 (CHEMBL5145822)
Ki
81±n/a nM
Citation
Juza, R; Vojtechova, I; Stefkova-Mazochova, K; Dehaen, W; Petrasek, T; Prchal, L; Kobrlova, T; Janousek, J; Vlcek, P; Mezeiova, E; Svozil, D; Karasova, JZ; Pejchal, J; Stark, H; Satala, G; Bojarski, AJ; Kubacka, M; Mogilski, S; Randakova, A; Musilek, K; Soukup, O; Korabecny, J Novel D Eur J Med Chem 232:0 (2022) [PubMed] ArticleMore Info.:
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
Inhibitor
Name:
BDBM50599915
Synonyms:
CHEMBL5170927
Type:
Small organic molecule
Emp. Form.:
C22H25N5O2
Mol. Mass.:
391.4662
SMILES:
O=C1CCc2ccc(OCCCN3CCN(CC3)c3ncccc3C#N)cc2N1
Structure:
