Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50556532
Substrate
n/a
Meas. Tech.
ChEMBL_2235850 (CHEMBL5149622)
Ki
7.0±n/a nM
Citation
 Gado, F; Ferrisi, R; Polini, B; Mohamed, KA; Ricardi, C; Lucarini, E; Carpi, S; Domenichini, F; Stevenson, LA; Rapposelli, S; Saccomanni, G; Nieri, P; Ortore, G; Pertwee, RG; Ghelardini, C; Di Cesare Mannelli, L; Chiellini, G; Laprairie, RB; Manera, C Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands. J Med Chem 65:9918-9938 (2022) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50556532
Synonyms:
CHEMBL4753891
Type:
Small organic molecule
Emp. Form.:
C21H24BrFN2O2
Mol. Mass.:
435.33
SMILES:
Cc1c(Br)cc(C(=O)NC2CCCCCC2)c(=O)n1Cc1ccc(F)cc1
Structure:
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