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Target
Melatonin receptor type 1A
Ligand
BDBM50188400
Substrate
n/a
Meas. Tech.
ChEMBL_362909 (CHEMBL866344)
Ki
8.2±n/a nM
Citation
 Tsotinis, A; Vlachou, M; Papahatjis, DP; Calogeropoulou, T; Nikas, SP; Garratt, PJ; Piccio, V; Vonhoff, S; Davidson, K; Teh, MT; Sugden, D Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines. J Med Chem 49:3509-19 (2006) [PubMed]  Article
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50188400
Synonyms:
CHEMBL207960 | N-(2-[5-methoxy-1H-indol-3-yl]-2,2-trimethyleneethyl)acetamide
Type:
Small organic molecule
Emp. Form.:
C16H20N2O2
Mol. Mass.:
272.3422
SMILES:
COc1ccc2[nH]cc(c2c1)C1(CNC(C)=O)CCC1
Structure:
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