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Target
Peroxisome proliferator-activated receptor alpha
Ligand
BDBM50189964
Substrate
n/a
Meas. Tech.
ChEMBL_393996 (CHEMBL854665)
EC50
1010±n/a nM
Citation
 Basséne, CE; Suzenet, F; Hennuyer, N; Staels, B; Caignard, DH; Dacquet, C; Renard, P; Guillaumet, G Studies towards the conception of new selective PPARbeta/delta ligands. Bioorg Med Chem Lett 16:4528-32 (2006) [PubMed]  Article
Target
Name:
Peroxisome proliferator-activated receptor alpha
Synonyms:
NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha)
Type:
Enzyme
Mol. Mass.:
52222.08
Organism:
Homo sapiens (Human)
Description:
Q07869
Residue:
468
Sequence:
MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
  
Inhibitor
Name:
BDBM50189964
Synonyms:
CHEMBL214394 | methyl 2-(2-methyl-4-(3-(2-propyl-4-(trifluoromethyl)phenoxy)propoxy)phenoxy)acetate
Type:
Small organic molecule
Emp. Form.:
C23H27F3O5
Mol. Mass.:
440.4527
SMILES:
CCCc1cc(ccc1OCCCOc1ccc(OCC(=O)OC)c(C)c1)C(F)(F)F
Structure:
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