Reaction Details  Report a problem with these data
Target
Cyclin-dependent kinase 1
Ligand
BDBM50553480
Substrate
n/a
Meas. Tech.
ChEMBL_2264662
IC50
50±n/a nM
Citation
 Huang, Z; Wang, T; Wang, C; Fan, Y CDK9 inhibitors in cancer research. RSC Med Chem 13:688-710 (2022) [PubMed]
Target
Name:
Cyclin-dependent kinase 1
Synonyms:
CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
34101.08
Organism:
Homo sapiens (Human)
Description:
P06493
Residue:
297
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
  
Inhibitor
Name:
BDBM50553480
Synonyms:
CHEMBL4741442
Type:
Small organic molecule
Emp. Form.:
C13H16BrN5O3S
Mol. Mass.:
402.267
SMILES:
C[C@H](CO)Nc1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1Br |r|
Structure:
Search PDB for entries with ligand similarity: