Reaction Details  Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50210268
Substrate
n/a
Meas. Tech.
ChEMBL_2265384
Ki
7.7±n/a nM
Citation
 Fallica, AN; Ciaffaglione, V; Modica, MN; Pittalą, V; Salerno, L; Amata, E; Marrazzo, A; Romeo, G; Intagliata, S Structure-activity relationships of mixed ? Bioorg Med Chem 73:0 (2022) [PubMed]
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50210268
Synonyms:
CHEMBL3984952
Type:
Small organic molecule
Emp. Form.:
C27H45N3O3
Mol. Mass.:
459.6645
SMILES:
COc1ccc(C)cc1NC(=O)OC1CC2CCCC(C1)N2CCCCCCCCCCN |TLB:22:21:16.18.17:20.13.14,THB:12:13:21:16.18.17|
Structure:
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