Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50607947
Substrate
n/a
Meas. Tech.
ChEMBL_2271928
Ki
14±n/a nM
Citation
 Mangiatordi, GF; Intranuovo, F; Delre, P; Abatematteo, FS; Abate, C; Niso, M; Creanza, TM; Ancona, N; Stefanachi, A; Contino, M Cannabinoid Receptor Subtype 2 (CB2R) in a Multitarget Approach: Perspective of an Innovative Strategy in Cancer and Neurodegeneration. J Med Chem 63:14448-14469 (2020) [PubMed]
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50607947
Synonyms:
CHEMBL1338358
Type:
Small organic molecule
Emp. Form.:
C23H21NO
Mol. Mass.:
327.4189
SMILES:
CCCn1c(C)c(C(=O)c2ccc3ccccc3c2)c2ccccc12
Structure:
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