Reaction Details  Report a problem with these data
Target
Dipeptidyl peptidase 9
Ligand
BDBM50612351
Substrate
n/a
Meas. Tech.
ChEMBL_2286836
Ki
>30000±n/a nM
Citation
 Kumar, S; Mittal, A; Mittal, A A review upon medicinal perspective and designing rationale of DPP-4 inhibitors. Bioorg Med Chem 46:0 (2021) [PubMed]
Target
Name:
Dipeptidyl peptidase 9
Synonyms:
DPP9 | DPP9_HUMAN | DPRP-2 | DPRP2 | Dipeptidyl peptidase 9 (DDP9) | Dipeptidyl peptidase 9 (DPP-9) | Dipeptidyl peptidase 9 (DPP9) | Dipeptidyl peptidase IV-related protein 2 | Dipeptidyl peptidase IX | Dipeptidyl peptidase IX (DDP-IX) | Dipeptidyl peptidase-like protein 9
Type:
Enzyme
Mol. Mass.:
98260.70
Organism:
Homo sapiens (Human)
Description:
Q86TI2
Residue:
863
Sequence:
MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL
  
Inhibitor
Name:
BDBM50612351
Synonyms:
CHEMBL5269774
Type:
Small organic molecule
Emp. Form.:
C20H14Cl3N3O
Mol. Mass.:
418.704
SMILES:
Cc1nc2cc(nn2c(c1CO)-c1ccc(Cl)cc1Cl)-c1ccccc1Cl |(4.83,4.06,;3.5,3.29,;2.17,4.06,;.84,3.29,;-.63,3.75,;-1.55,2.5,;-.67,1.28,;.84,1.74,;2.17,.98,;3.5,1.75,;4.83,.98,;6.17,1.75,;2.17,-.56,;.84,-1.33,;.84,-2.87,;2.17,-3.63,;2.17,-5.17,;3.51,-2.86,;3.51,-1.33,;4.84,-.56,;-3.09,2.5,;-3.86,1.17,;-5.4,1.17,;-6.17,2.5,;-5.4,3.84,;-3.86,3.84,;-3.09,5.17,)|
Structure:
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