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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50612564
Substrate
n/a
Meas. Tech.
ChEMBL_2288894
IC50
64800±n/a nM
Citation
 Provensi, G; Costa, A; Rani, B; Becagli, MV; Vaiano, F; Passani, MB; Tanini, D; Capperucci, A; Carradori, S; Petzer, JP; Petzer, A; Vullo, D; Costantino, G; Blandina, P; Angeli, A; Supuran, CT New ?-arylchalcogeno amines with procognitive properties targeting Carbonic Anhydrases and Monoamine Oxidases. Eur J Med Chem 244:0 (2022) [PubMed]
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50612564
Synonyms:
CHEMBL5286089
Type:
Small organic molecule
Emp. Form.:
C9H12BrNS
Mol. Mass.:
246.167
SMILES:
CC(N)CSc1ccccc1Br
Structure:
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