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Target
Peptidyl-prolyl cis-trans isomerase A
Ligand
BDBM50613629
Substrate
n/a
Meas. Tech.
ChEMBL_2292744
IC50
14±n/a nM
Citation
 Dunyak, BM; Gestwicki, JE Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds. J Med Chem 59:9622-9644 (2016) [PubMed]
Target
Name:
Peptidyl-prolyl cis-trans isomerase A
Synonyms:
CYPA | CYPA PPIase | Cyclophilin A | Cyclosporin A-binding protein | PPIA | PPIA_HUMAN | PPIase A | Peptidyl-prolyl cis-trans isomerase A | Rotamase A
Type:
Protein
Mol. Mass.:
18015.32
Organism:
Homo sapiens (Human)
Description:
P62937
Residue:
165
Sequence:
MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
  
Inhibitor
Name:
BDBM50613629
Synonyms:
CHEMBL5268140
Type:
Small organic molecule
Emp. Form.:
C20H17N3O4
Mol. Mass.:
363.3667
SMILES:
[O-][N+](=O)c1ccc(NC(=O)Nc2ccccc2OCc2ccccc2)cc1
Structure:
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