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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM7461
Substrate
n/a
Meas. Tech.
ChEMBL_2296037
Ki
7860±n/a nM
Citation
 An, S; Ko, H; Jang, H; Park, IG; Ahn, S; Hwang, SY; Gong, J; Oh, S; Kwak, SY; Lee, Y; Kim, H; Noh, M Prenylated Chrysin Derivatives as Partial PPAR? Agonists with Adiponectin Secretion-Inducing Activity. ACS Med Chem Lett 14:425-431 (2023) [PubMed]
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM7461
Synonyms:
5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihydroxy-2-phenyl-chromen-4-one | 5,7-dihydroxyflavone | CHEMBL117 | chrysin | cid_5281607
Type:
Small organic molecule
Emp. Form.:
C15H10O4
Mol. Mass.:
254.2375
SMILES:
Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccccc1
Structure:
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