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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50200957
Substrate
n/a
Meas. Tech.
ChEMBL_422734 (CHEMBL854830)
Ki
31000±n/a nM
Citation
 Whiting, M; Tripp, JC; Lin, YC; Lindstrom, W; Olson, AJ; Elder, JH; Sharpless, KB; Fokin, VV Rapid discovery and structure-activity profiling of novel inhibitors of human immunodeficiency virus type 1 protease enabled by the copper(I)-catalyzed synthesis of 1,2,3-triazoles and their further functionalization. J Med Chem 49:7697-710 (2006) [PubMed]  Article
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50200957
Synonyms:
CHEMBL216912 | [(1S,2S)-2-azido-1,2-dibenzylethyl]carbamic acid tert-butyl ester
Type:
Small organic molecule
Emp. Form.:
C21H26N4O2
Mol. Mass.:
366.4567
SMILES:
CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](Cc1ccccc1)N=[N+]=[N-] |r|
Structure:
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