Reaction Details  Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM50615162
Substrate
n/a
Meas. Tech.
ChEMBL_2299835
IC50
24800±n/a nM
Citation
 Fernandes, GFS; Scarim, CB; Kim, SH; Wu, J; Castagnolo, D Oxazolidinones as versatile scaffolds in medicinal chemistry. RSC Med Chem 14:823-847 (2023) [PubMed]
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50615162
Synonyms:
CHEMBL5286328
Type:
Small organic molecule
Emp. Form.:
C10H15NO5
Mol. Mass.:
229.2298
SMILES:
[H][C@]12C[C@]3([H])OC(C)(C)O[C@]3([H])[C@@H](O)[C@@]1([H])NC(=O)O2 |r|
Structure:
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