Reaction Details  Report a problem with these data
Target
C-X-C chemokine receptor type 4
Ligand
BDBM50615201
Substrate
n/a
Meas. Tech.
ChEMBL_2300253
Ki
180±n/a nM
Citation
 Arimont, M; Sun, SL; Leurs, R; Smit, M; de Esch, IJP; de Graaf, C Structural Analysis of Chemokine Receptor-Ligand Interactions. J Med Chem 60:4735-4779 (2017) [PubMed]
Target
Name:
C-X-C chemokine receptor type 4
Synonyms:
C-X-C chemokine receptor type 4 | C-X-C chemokine receptor type 4 (CXCR4) | CD_antigen=CD184 | CXC-R4 | CXCR-4 | CXCR4 | CXCR4_HUMAN | FB22 | Fusin | HM89 | LCR1 | LESTR | Leukocyte-derived seven transmembrane domain receptor | NPYRL | SDF-1 receptor | Stromal cell-derived factor 1 receptor
Type:
Enzyme
Mol. Mass.:
39754.61
Organism:
Homo sapiens (Human)
Description:
P61073
Residue:
352
Sequence:
MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
  
Inhibitor
Name:
BDBM50615201
Synonyms:
1,3-Di(1,4,8,11-Tetraazacyclotetradecanyl)Propane | CHEMBL28967
Type:
Small organic molecule
Emp. Form.:
C23H52N8
Mol. Mass.:
440.7126
SMILES:
C(CN1CCCNCCNCCCNCC1)CN1CCCNCCNCCCNCC1
Structure:
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