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Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM50615279
Substrate
n/a
Meas. Tech.
ChEMBL_2301975
IC50
330±n/a nM
Citation
 Floresta, G; Pistarà, V; Amata, E; Dichiara, M; Marrazzo, A; Prezzavento, O; Rescifina, A Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review. Eur J Med Chem 138:854-873 (2017) [PubMed]
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM50615279
Synonyms:
CHEMBL5285216
Type:
Small organic molecule
Emp. Form.:
C31H25FN2O3
Mol. Mass.:
492.5402
SMILES:
CCc1c(c(nn1-c1ccccc1-c1cccc(OCC(O)=O)c1)-c1ccc(F)cc1)-c1ccccc1
Structure:
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