Reaction Details  Report a problem with these data
Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM50152859
Substrate
n/a
Meas. Tech.
ChEMBL_2301977
IC50
4700±n/a nM
Citation
 Floresta, G; Pistarà, V; Amata, E; Dichiara, M; Marrazzo, A; Prezzavento, O; Rescifina, A Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review. Eur J Med Chem 138:854-873 (2017) [PubMed]
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM50152859
Synonyms:
3-(6-Fluoro-indole-1-sulfonyl)-thiophene-2-carboxylic acid | CHEMBL184846
Type:
Small organic molecule
Emp. Form.:
C13H8FNO4S2
Mol. Mass.:
325.335
SMILES:
OC(=O)c1sccc1S(=O)(=O)n1ccc2ccc(F)cc12
Structure:
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