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Target
Quinone oxidoreductase
Ligand
BDBM50204915
Substrate
n/a
Meas. Tech.
ChEMBL_428131 (CHEMBL915768)
IC50
>50000±n/a nM
Citation
 Krick, A; Kehraus, S; Gerhäuser, C; Klimo, K; Nieger, M; Maier, A; Fiebig, HH; Atodiresei, I; Raabe, G; Fleischhauer, J; König, GM Potential cancer chemopreventive in vitro activities of monomeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis. J Nat Prod 70:353-60 (2007) [PubMed]  Article
Target
Name:
Quinone oxidoreductase
Synonyms:
Cryz | QOR_MOUSE
Type:
PROTEIN
Mol. Mass.:
35275.21
Organism:
Mus musculus
Description:
ChEMBL_428131
Residue:
331
Sequence:
MATGQKLMRAIRVFEFGGPEVLKLQSDVVVPVPQSHQVLIKVHACGVNPVETYIRSGAYSRKPALPYTPGSDVAGIIESVGDKVSAFKKGDRVFCYSTVSGGYAEFALAADDTIYPLPETLNFRQGAALGIPYFTACRALFHSARARAGESVLVHGASGGVGLATCQIARAHGLKVLGTAGSEEGKKLVLQNGAHEVFNHKEANYIDKIKMSVGDKDKGVDVIIEMLANENLSNDLKLLSHGGRVVVVGCRGPIEINPRDTMAKETSIIGVSLSSSTKEEFQQFAGLLQAGIEKGWVKPVIGSEYPLEKAAQAHEDIIHGSGKTGKMILLL
  
Inhibitor
Name:
BDBM50204915
Synonyms:
(1S,3S,4S,4aS,9aS)-1,4,8-trihydroxy-3,4a-dimethyl-1,2,3,4,4a,9a-hexahydro-9H-xanthen-9-one | CHEMBL223073
Type:
Small organic molecule
Emp. Form.:
C15H18O5
Mol. Mass.:
278.3004
SMILES:
C[C@H]1C[C@H](O)[C@@H]2C(=O)c3c(O)cccc3O[C@]2(C)[C@H]1O
Structure:
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