Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50217075
Substrate
n/a
Meas. Tech.
ChEMBL_440456 (CHEMBL890771)
Ki
>10000±n/a nM
Citation
 Minutolo, F; Cascio, MG; Carboni, I; Bisogno, T; Prota, G; Bertini, S; Digiacomo, M; Bifulco, M; Di Marzo, V; Macchia, M Metabolically labile cannabinoid esters: a 'soft drug' approach for the development of cannabinoid-based therapeutic drugs. Bioorg Med Chem Lett 17:4878-81 (2007) [PubMed]  Article
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50217075
Synonyms:
2,6-dimethoxy-3',5'-dimethyl-biphenyl-4-carboxylic acid | CHEMBL228429
Type:
Small organic molecule
Emp. Form.:
C17H18O4
Mol. Mass.:
286.3224
SMILES:
COc1cc(cc(OC)c1-c1cc(C)cc(C)c1)C(O)=O
Structure:
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